In cytoreductive surgery and hyperthermic intraperitoneal chemotherapy (HIPEC), visible cancerous tumors are first removed from the abdominal cavity surgically. The cavity is then bathed with hot chemotherapy — heated to 42 degrees Celsius — to kill any microscopic cancer cells that remain.
What is intraperitoneal chemo?
Intraperitoneal (IP) chemotherapy is a way to put some of your chemotherapy into your abdomen (also called the peritoneal cavity) rather than into a vein. By putting the chemotherapy into your abdomen, the drugs can treat cancer cells directly.
What is the purpose of cytoreductive debulking surgery for ovarian cancer?
Debulking cytoreductive surgery is a common treatment procedure for ovarian cancer. The goal of debulking is to remove as much cancerous tissue in the patient’s abdomen as possible, leaving behind no tumor nodules that measure more than 1 centimeter in diameter.
Who performs cytoreductive surgery?
Surgical Oncologists and Gynecological Oncologists specialize in treating cancer patients, performing more complex and less common procedures. Cytoreductive Surgery is aggressive removal of all visible tumors on peritoneal surfaces that requires expertise….
What is intraperitoneal surgery?
Hyperthermic intraperitoneal chemotherapy (HIPEC) surgery is a two-step procedure that treats certain cancers in the abdomen. Cancerous tumors are surgically removed, and then heated chemotherapy drugs are applied directly inside the abdomen to eliminate the remaining cancerous cells.
Is cytoreductive surgery the same as debulking?
It is usually achieved by surgical removal. When performed for curative intent, it is a different procedure, which is called surgical debulking of tumors is known as cytoreduction or cytoreductive surgery (CRS); “cytoreduction” refers to reducing the number of tumor cells.
What is interval debulking?
Types of interventions. Treatment: Interval debulking surgery (IDS), defined as secondary surgery which is performed after two to four cycles of neoadjuvant chemotherapy (NAC) or induction chemotherapy, to remove the bulk of the tumour, and followed by adjuvant chemotherapy of the same type.
Who qualifies for HIPEC?
It is designed for patients 18-75 years of age who have peritoneal surface disease (PSD) due to colorectal cancer or high-grade appendiceal cancer.