Conclusions: Flavored intravenous ondansetron administered orally is a safe and an effective option and can be considered in the absence of the oral forms of the drug.
How is Zofran Injection administered?
For management of highly emetogenic chemotherapy, a dose of 8 mg of Zofran may be administered by slow intravenous injection in not less than 30 seconds, or intramuscular injection immediately before chemotherapy, followed by two further intravenous or Page 7 intramuscular doses of 8 mg two to four hours apart, or by a …
Is there oral Zofran?
ZOFRAN ODT tablets are a freeze-dried, orally administered formulation of ondansetron which disintegrates on the tongue and does not require water to aid dissolution or swallowing. Each 5 mL of ZOFRAN oral solution contains 5 mg of ondansetron hydrochloride dihydrate equivalent to 4 mg of ondansetron.
Can you drink Zofran?
Although Zofran and alcohol do not directly interact, Zofran has many common side effects that could be worsened by alcohol, such as drowsiness or dizziness. If you take Zofran, check with your healthcare provider regarding whether you can safely drink alcohol.
Is Zofran oral or IV?
The recommended adult intravenous dosage of ZOFRAN is three 0.15-mg/kg doses up to a maximum of 16 mg per dose [see CLINICAL PHARMACOLOGY]. The first dose is infused over 15 minutes beginning 30 minutes before the start of emetogenic chemotherapy.
Can IV meds be given orally?
Certain drugs may be given by IV administration because if you took them orally (by mouth), enzymes in your stomach or liver would break them down. This would prevent the drugs from working well when they’re finally sent to your bloodstream.
Where do you give a Zofran injection?
Ondansetron comes as a solution (liquid) to be injected intravenously (into a vein) or intramuscularly (into a muscle) by a health care provider in a hospital or clinic. When ondansetron is used to prevent nausea and vomiting caused by chemotherapy, it is usually given 30 minutes before the start of chemotherapy.
Can Zofran be given SQ?
Ondansetron is not labeled for subcutaneous administration because the medication is formulated as a sterile, aqueous isotonic solution buffered with citrate, which can cause allergic or toxic reactions to the skin due to its acidic pH.
What is Ondansetron Injection used for?
Ondansetron injection is used to prevent the nausea and vomiting that may occur after treatment with cancer medicines (chemotherapy or radiation), including high-dose cisplatin. This medicine is also used to prevent and treat nausea and vomiting that may happen after surgery.
Can Ondansetron be given IV?
Adults: For the prevention of PONV ondansetron can be administered by intravenous injection or other dosage forms. Ondansetron may be administered as a single dose of 4 mg given by slow intravenous injection at induction of anaesthesia.
